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GLP-1 (glucagon-like peptide-1) is a natural hormone released after meals that: Stimulates insulin release Reduces glucagon (sugar-raising hormone) Slows stomach emptying Promotes fullness and appetite control Ozempic mimics this hormone in a long-acting injectable form, taken once weekly

Glucagon-like peptide-1 attenuates endothelial barrier injury in diabetes via cAMP/PKA mediated down-regulation of MLC phosphorylation

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Cumulative evidence suggests that vascular inflammation occurs during AD with higher levels of adhesion molecules associated with endothelial cell activation such as VCAM-1, ICAM-1, E-selectin, and P-selectin found in plasma samples from AD patients (Nielsen et al., 2007