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Warnings and Precautions Anaphylaxis and Serious Hypersensitivity Reactions: In clinical trials of lixisenatide, there have been cases of anaphylaxis and other serious hypersensitivity reactions including angioedema

It might also help to slightly increase healthy fats in your diet (e.g., a little olive oil, nuts, etc.), as very low-fat diets can sometimes worsen constipation

Ultimately, FDA-approved drugs have a more airtight safety profile than custom drugs made in the pharmacy setting