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Furthermore, gene knockdown of Cav-1 suppressed the anti-inflammatory effects of the DPP-4 inhibitor teneligliptin in human monocyte/macrophage U937, showing that teneligliptin needs to bind Cav-1 to exert its effects (54)

Within the framework of fundamental medicine, the approach proposed by integrative physiology can be the only correct way to view the pathological state of an organism, not from the perspective of the presence of a specific disease or multiple comorbid conditions, but as a complex and unified process based on various links of pathogenesis

On judging the significance of differences by examining the overlap between confidence intervals