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Some patients benefit from modest dose increments or adjusted dosing schedules

In addition, collecting data from individuals who are undergoing weight reduction or participating in diet-induced weight loss programs could offer additional understanding of the underlying mechanisms involved [66]

Current Evidence and Regulatory Guidance from MHRA and EMA Regulatory authorities including the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK and the European Medicines Agency (EMA) have carefully reviewed available evidence regarding GLP-1 agonists and mental health concerns
