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The results of our analysis confirm the lack of any benefit by DPP-4 inhibitors on cardiorenal outcomes in people with type 2 diabetes [22]

In the intestine, GLP-1 production colocalizes with the production of glucose-dependent insulinotropic polypeptide (GIP) or peptide YY (PYY), and they share physiological properties, such as glucose control (Holst, 2007)

These medicines demonstrated superior tolerability profiles owing to their less impact on gastric emptying, resulting in fewer gastrointestinal side effects

Incretins Introduction Type 2 diabetes may result from a variety of conditions including -cell dysfunction, where insulin is not produced, and/or due to insulin resistance, in both cases leading to hyperglycemia, and complications in both small and large blood vessels (Silberstein, 2013)