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Second-generation: cilofexor (GS-9674), tropifexor (LJN452) Cilofexor is a potent, selective, nonsteroidal agonist of FXR that predominantly activates intestinal FXR without involvement of the enterohepatic circulation
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Jardiance belongs to the SGLT2 inhibitor family, a class approved primarily for type 2 diabetes management

doi: 10.1111/dom.13053
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