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Might widespread GLP-1 adoption among older adults trade a near-term obesity epidemic for a long-term frailty epidemic
Some individuals also experience tachyphylaxisa gradual decline in medication effectiveness over weeks or monthsdue to receptor downregulation
The weight gain was not dramatic overnight, but it was enough that I noticed it in my clothes, my energy, and how I felt overall
Quantification of the effect of energy imbalance on bodyweight
