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Description
Through this integrated mechanism of action, mazdutide represents a new approach to treating obesity and related metabolic diseases, targeting not only how much patients eat, but also how efficiently their bodies burn and store energy

Meal-anticipatory glucagon-like peptide-1 secretion in rats

Unlike sulfonylureas, which stimulate insulin secretion independently of blood glucose and can lead to hypoglycemia, GLP-1RAs improve glycemic control in a glucose-dependent manner, thereby minimizing the risk of hypoglycemia

[33] [34] [35] This was a landmark event which proved that targeting the GLP-1 receptor was a viable strategy and inspired other pharmaceutical companies to focus their research and development on that receptor
