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Second, long-term safety with regard to adipose tissue loss and, in particular, muscle mass loss must be determined, as chronic pulmonary diseases due to continuous inflammation are known to lead to sarcopenia

Filingeri noted that this research study was designed to further examine changes in weight, body fat mass, and muscle mass in patients taking incretin medications. We found that, under close supervision and regular follow-up from an obesity medicine specialist, patients were able to lose fat mass with only a minimal decline in muscle mass. Alexandra Filingeri, DCN, RCN Filingeri pointed out that the results of this study cannot be generalized to patients receiving medication via telemedicine without routine body composition analysis, nor can they be generalized to in-person visits without utilizing body composition analysis

Risk appears highest at the 2.4 mg dose

For researchers specifically interested in the intersection of weight loss and anti-aging benefits, the overlap between metabolic peptides and longevity compounds represents a growing area of investigation