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Below I summarized a breakdown of the key mechanisms, drawn from robust preclinical evidence across models: Spinal Microglial Activation and -Endorphin Pathway: Liraglutide was shown to bind GLP-1 receptors on spinal microglia, sparking an anti-inflammatory cascade

Acta neuropsychiatrica

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[DOI] [PubMed] [Google Scholar] 4.Hernandez AF, Green JB, Janmohamed S, et al