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Reversal phase: Following osteoclast-mediated resorption, the Howship lacunae are covered with a partially digested demineralized collagen matrix (Saftig et al., 1998)
[DOI] [PubMed] [Google Scholar] 930.Irwin N., Flatt P.R
doi: 10.1007/s00125-006-0510-2
These outcomes lead to the remodeling of the extracellular matrix, oxidative stress, inflammation, cardiomyocyte apoptosis, fibrosis, and metabolic abnormalities [55]
