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What the Research Says About SSRIs and GLP-1 Together A 2022 analysis published in Diabetes, Obesity and Metabolism examined GLP-1 receptor agonist use in patients with comorbid depression and found that semaglutide treatment was not associated with worsening depressive symptoms
Tirzepatide can cause higher rates of injection site reactions
Gastrointestinal symptoms Nausea, vomiting, diarrhea, constipation, abdominal discomfort, bloating
Cholecystitis and cholelithiasis (gallstones) occur more frequently in people losing weight rapidly, regardless of the method
