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The metallic taste may be due to changes in saliva production, mild ketosis or bile reflux

Side effects are broadly similar to other GLP-1 class medications primarily gastrointestinal effects including nausea, diarrhea, and constipation during dose escalation, which are typically transient

According to FDA communications: "The FDA does not verify the safety, effectiveness, or quality of compounded drugs before they are marketed." Compounded semaglutide formulations have not undergone independent clinical trials as finished products

ALT and AST reductions of 20 to 40 percent occur commonly, reflecting improved hepatic steatosis and inflammation