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Fatty acidbinding proteins (FABPs) are small cytoplasmic proteins involved in intracellular lipid metabolisms such as fatty acid uptake, transport to mitochondria or peroxisome for oxidation, lipid synthesis, storage in lipid droplets, and regulation of nuclear receptors 52

Zepbound, which mimics a second hormone called gastric inhibitory polypeptide (GIP) in addition to the GLP-1, comes in an injectable, prefilled, single-use pen for just over $1,000 per pen

Real-world discontinuation rates for GLP-1RAs range from 17%35% in the first year, varying by drug and country (221)

Different medicines within this class have varying receptor binding profiles and pharmacokinetic properties