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Safety and tolerability of RYBELSUS were evaluated across 10 different clinical trials 1-4,a Safety and tolerability of RYBELSUS were evaluated across 10 different clinical trials 1-4,a The most frequently reported adverse reactions were GI disorders, including nausea, abdominal pain, and diarrhea Nausea, vomiting, and/or diarrhea occurred mostly during dose escalation 4% and 8% of patients discontinued RYBELSUS 7 mg and 14 mg, respectively, due to GI adverse reactions, compared to 1% of patients receiving placebo GI=gastrointestinal

"One hypothesis is that [with] COVIDthe illness as opposed to the virusthe badness is really related to inflammation, and obesity is an inflammatory state, as is diabetes," John Buse, a medical professor and director of the University of North Carolina's Diabetes Care Center, who has co-authored a study about the interaction of COVID with diabetes, told Newsweek

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Writing in The Lancet Psychiatry, the authors said GLP-1 receptor agonists semaglutide and liraglutide, sold under the brand name Saxenda, were associated with lower risk of worsening mental illness compared to non-use of this type of drug