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Their ability to suppress appetite, regulate blood sugar, and reduce cravings addresses multiple facets of weight management

GLP-1R alone, as activated by semaglutide, primarily signals through Gs-cAMP and PI3K pathways in beta-cell lines
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Furthermore, some reported being more sensitive to sweet or sour tastes, and more sensitive to food textures, although these were from answers to open-ended questions and not formally measured in the study