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Chronic stress, through activation of the hypothalamicpituitaryadrenal (HPA) axis and elevation of cortisol, promotes visceral fat accumulation and emotional hyperphagia, particularly in individuals with high cortisol reactivity [32]

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Medications that enhance GLP-1 activity offer a promising solution for individuals struggling with obesity

Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): A double-blind, randomised, phase 3 trial