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50,000 crore roughly US$6 billion once the domestic market, neighbouring emerging economies, and a small but lucrative set of regulated geographies are added together

N Engl J Med 375:18341844 Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB, Chan JC, Choi J, Gustavson SM, Iqbal N, Maggioni AP, Marso SP, hman P, Pagidipati NJ, Poulter N, Ramachandran A, Zinman B, Hernandez AF (2017) EXSCEL Study Group

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Conversely, some patients experience constipation , reflecting the variable effects of GLP-1 receptor agonists on different individuals' gastrointestinal motility