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At the highest doses, retatrutide GI side effect rates are modestly higher than the other two medications
10.1006/geno.1995.9937 Genomics 174 YamaneS.HaradaN.HamasakiA.MuraokaA.JooE.SuzukiK.et al (2012)
78 Augmented cAMP signaling might not only strengthen classical cAMP/PKA pathways but could also modulate cAMP/Epac-dependent pathways, including PI3K/Akt, which have been associated with aspects of cellular survival, mitochondrial bioenergetics, and autophagy in preclinical studies
Hisadome et al., 2010)
