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Six months later I am at 160 lb, down 26 lb, and the number matters less to me than the fact that food went back to being food instead of a running argument

Participants in the 1-mg GLP-3R group experienced an average weight reduction of 7.2%, while those receiving 4 mg with an initial dose of 2 mg lost 11.8%, and those with an initial dose of 4 mg lost 13.9%

Step 2: estimate treatment duration Plan for a minimum of 12 months

Whats happening: No visible vascular damage yet Possible early neurodegeneration (not visible on standard exams) Blood glucose levels may still be damaging retinal cells Management focus: Optimize diabetes control (target HbA1c 6-7%) Annual comprehensive dilated eye exams Establish baseline retinal imaging Stage 2: Mild Nonproliferative Diabetic Retinopathy (NPDR) The earliest clinically detectable stage, characterized by microaneurysmstiny bulges in retinal blood vessels