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Description
Tirzepatide vs Semaglutide for Metabolic Research: What the Head-to-Head Evidence Shows The most definitive head-to-head data comes from SURMOUNT-5, published in the New England Journal of Medicine in 2025

Any other medications you are taking

Tirzepatide carries a boxed warning about thyroid C-cell tumors based on animal studies

A structured, clinician-guided taper when you reach your goal
