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Some research indicates berberine might boost GLP-1 levels naturally, though evidence remains preliminary

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[DOI] [PubMed] [Google Scholar] Reneke JE, Blumer KJ, Courchesne WE, Thorner J

In the Liraglutide Effect and Action in Diabetes trial (LEAD-3), GLP-1RA liraglutide treatment significantly reduced body fat, but there was no significant change in lean body mass
