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K.FaragoN.FurdanS.KovacsB.LovasS.et al

Glucagon-like Peptide 1 Receptor Agonists, Diabetic Retinopathy and Angiogenesis: The AngioSafe Type 2 Diabetes Study

While there are abnormalities in vagal innervation, contrary to expectation, the relationship of delayed gastric emptying with autonomic dysfunction, as assessed by cardiovascular reflex tests, is weak [1, 2]

Accordingly, people with type 2 diabetes, cardiovascular disease, heart failure, or chronic kidney disease should be treated appropriately with an SGLT-2 inhibitor or GLP-1RA, even because more adults with type 2 diabetes in the US have suboptimal glycemic control now compared to 10 years ago, associated with a resurgence in vascular diabetic complications [32]