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This finding is highly relevant because amputations entail negative impacts on the health of our patients, such as disability and loss of autonomy, and on the health care system due to associated high costs.34 Thus, GLP-1RAs could be considered as part of the optimal medical therapy for patients with T2DM and PAD to reduce the risk of PAD-related events

The Efficacy and Safety of Liraglutide 3.0 mg for Weight Management in Obese Non-Diabetic Saudi Outpatients

In general, a symptomatic decrease in blood glucose was uncommon (less than 8% in all groups that received oral semaglutide)

But they have different approved uses