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SUSTAIN 5 (Rodbard 2018, J Clin Endocrinol Metab) tested semaglutide added to basal insulin and showed significant hypoglycemia reduction when insulin doses were proactively lowered

When medications cost $800 to $1,400 per month without coverage, patients stockpile nine-month supplies of compounded alternatives when available, time prescriptions around insurance changes, and calculate whether budgets freed up by eating less can offset drug costs

Testosterone therapy can influence body composition by increasing lean muscle mass and potentially affecting insulin sensitivity