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Description
Safety was monitored in those who took at least one dose of the study medication

Compounded medications are not FDA-approved finished drug products and are not reviewed by FDA for safety, effectiveness, or quality before marketing

Patients with significant comorbidities, prior medication side effects, or requiring rapid dose escalation should discuss with a provider whether a personalized, potentially higher-dose approach justifies the cost difference

doi: 10.1056/NEJMoa1504720 36 HolstJJ
