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Description
Most side effects diminish as your body adjusts to each dose level, which is one reason the escalation schedule spans 20 weeks rather than jumping immediately to the target dose

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Enhanced insulin secretion : GIP and GLP-1 stimulate insulin release through partially distinct intracellular mechanisms

If a previously comfortable injection suddenly causes burning, redness, or significant irritation at the thigh injection site, the medication itself may be the issue rather than your technique
