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That suggests GLP-1s might help symptoms surrounding lipedema, such as: Improved mobility Less systemic inflammation Reduced stress on joints Better blood sugar and insulin regulation However GLP-1 has not been shown to remove lipedema fat Women may see weight loss everywhere except their legs, which can ironically make lipedema more obvious

People who live with this condition may already have sensitive or inflamed skin, which can make it more difficult to handle additional triggers

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