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Description
An observational Indian study in GLP-1 users reported that about 4 in 10 people experienced GI side effects, with nausea being the most common, followed by vomiting, diarrhoea, and constipation

However, these factors are secondary to temperature

Li Q, Tuo X, Li B, Deng Z, Qiu Y, Xie H

173,174 Collectively, these mechanisms of action make GLP-1 RAs an important therapeutic agent for the treatment of IR and for improving glycemic control