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In our study, pretreatment HbA1C level was the dominant factor that affected GLP-1 M treatment outcome in the current analysis
We assessed the therapeutic effects of in vivo genome-editing, including the suppression of body weight gain and improvement of blood glucose profiles (Fig
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On the other hand, the fact that the mean HbA1c level in our subjects (5.8%) is near normal values could also hamper the finding of a more meaningful effect
