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Orals are not just another formulation. They are the first credible attempt to make GLP-1 mass-market scalable in the way statins or antihypertensives wereif efficacy, safety, and supply can hold

For patients experiencing diarrhea or abdominal discomfort, morning administration may be preferable, as it allows symptoms to manifest during daytime hours when patients have easier access to bathroom facilities and can manage hydration more effectively

Retatrutides 24.2% at 12 mg over 48 weeks represents approximately 60% greater efficacy in a shorter timeframe

Paulina Salminen of Finlands Turku University Hospital and her colleagues
