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Injection site reactions are the most commonly reported dermatological effects with subcutaneous semaglutide (Ozempic and Wegovy) and typically present as redness, itching, bruising, or mild swelling at the site of administration

double-blind double-dummy Patients 1864 adult patients with type 2 diabetes on metformin alone or metformin with a sulfonylurea Treatment arms Patients were randomized to RYBELSUS 3 mg (n=466), RYBELSUS 7 mg (n=465), RYBELSUS 14 mg (n=465), or Januvia 100 mg (n=467), all once daily

Potential concerns include: Unpredictable effects on blood sugar and metabolism Greater potential for Retatrutide interactions with other medicines Difficulty determining which peptide is responsible if side effects occur Unknown long-term Retatrutide safety when combined with growth hormone peptides Additional risks when products are obtained from unregulated sources, where purity, sterility and accurate dosing cannot be guaranteed Who Should Exercise Extra Caution