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For individuals managing weight or blood glucose stability, this profile is significantly different from sucralose, aspartame, or stevia, which do not reliably stimulate GLP-1 secretion

In a study of 80 obese people with type 2 diabetes receiving semaglutide and dulaglutide, a 20% reduction in the thickness of EAT was observed (62) One meta-analysis demonstrated the cardioprotective effects of GLP-1 RAs, showing reductions in blood pressure and lipid profile, with a significant increase in HDL levels (63)

Holdsworth CD, Turner D, McIntyre N

This is a document submitted by your provider for your insurance company to determine whether they think a treatment is necessary before agreeing to cover it