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Seetharaman R, Monteiro R, Maradia J, Tripathi R

First, most studies utilize menstrual bleeding as a proxy for ovulation rather than mid-luteal progesterone, serial ultrasonography, or other gold-standard confirmations

Rare but Serious Side Effects to Monitor Both tirzepatide and semaglutide carry a black-box warning for thyroid C-cell tumors based on animal studies, though no such tumors have been confirmed in human users

Nausea and vomiting appear to be most common when people overeat or potentially overeat fat which also slows down gastric emptying and could further worsen symptoms
