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Cardiovascular outcomes included hospitalization for heart failure (HHF), all-cause mortality, HHF plus all-cause mortality, myocardial infarction (MI), stroke, and modified major adverse cardiovascular events (MACEs)

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Both types thrive in concentrated urine, which is a common outcome when persistent nausea or vomiting reduces overall fluid intake

Typically, these medications are started at a low dosage, which is gradually increased to a maintenance level, allowing the body to tolerate any potential side effects