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When caloric intake is substantially reduceda common occurrence given semaglutide's potent effects on appetite and satietythe body shifts from primarily using glucose for energy to breaking down stored fat
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Peripheral glucose metabolism in human hyperthyroidism
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Start the medication first, stabilize on it, then add Pendulum at half dose
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The authors attribute these results to the increase in GLP-1, although it was not directly measured (Furrer, Kaufmann, Tschuor, Reusch & Lutz, 2010)