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Studies suggest that tirzepatide can lead to greater weight loss than Ozempic , with some patients losing more than 20% of their body weight

however, if you start to gain back the weight youve lost, you may need to resume a once-weekly injection of semaglutide for weight management

19 The mean change in body weight from baseline to week 68 was 14.9% in the semaglutide group compared with 2.4% with placebo, for an estimated treatment difference of 12.4 percentage points (95% confidence interval [CI], 13.4 to 11.5