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This activation triggers downstream signaling pathways, leading to the phosphorylation of STAT proteins, thereby regulating the expression of a series of genes and affecting cell function and physiological activity

Importantly, our analysis extends previous work by concurrently evaluating multiple cardiometabolic domains and identifying temporal and drug-specific differences in rebound severity

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Thermogenic dietary supplements can provide functional benefits through various biological pathways, such as activating uncoupling proteins, inhibiting phosphodiesterase, or targeting 2 -adrenergic receptor agonists to increase energy expenditure and activate brown adipose tissue [75]