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This compound presented a 350-fold reduction in potency at human GLP-1R, using the cAMP accumulation assay, to 30 nM as compared to 87 pM for the non-glycosylated Ab#2_GLP1 fusion

[ Mendoza, A., Navarrete-Ramrez, P., Hernndez-Puga, G., Villalobos, P., Holzer, G., Renaud, J.P., Laudet, V., & Orozco, A

Acknowledgements The authors thank Michael Bonar, Creative Director at the Leicester Diabetes Centre, for the original figure concept

Get Started Now How it Helps Manages blood sugar Semaglutide may help regulate blood sugar levels by increasing insulin secretion and decreasing glucagon release
