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The study included 80 participants divided between cases (PSO + Mediterranean Diet [MeDi]) and controls (only MeDi), all subjected to an extensive set of neurological assessments following a year of their respective interventions

These changes were accompanied by preservation of structural proteins including aggrecan and collagen II, along with reduced caspase-3mediated apoptosis, suggesting a coordinated reduction in glycation-driven cellular stress and tissue degradation

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Surgical Procedures For individuals struggling with severe obesity, medical procedures like gastric bypass or endoscopic treatments may be an option