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Wolfram syndrome is a rare autosomal recessive disorder that commonly manifests itself in the form of diabetes mellitus, optic nerve atrophy, central diabetes insipidus, sensorineural deafness, urinary tract problems and progressive neurologic difficulties

The meal plan emphasizes low-glycemic, nutrient-dense foods, including lean proteins, whole grains, non-starchy vegetables, and healthy fats, with a focus on high-fiber foods to aid digestion and stabilize blood glucose

Most long-acting GLP-1 receptor agonists (including semaglutide, liraglutide, and dulaglutide) also carry this warning, though not every short-acting agent does

Broide, E., Bloch, O., Ben-Yehudah, G., Cantrell, D., Shirin, H., & Rapoport, M