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These new treatment modalities may provide an option in refractory gastroparesis with the adage of reduced morbidity compared to surgical treatments

Anti-obesity pharmacological agents for polycystic ovary syndrome: a systematic review and meta-analysis to inform the 2023 international evidence-based guideline

Because retatrutide combines all three mechanisms in one molecule, its trials have so far reported a larger average weight-loss effect than mazdutides, though the two have never been tested against each other directly, so that comparison is drawn across separate trials rather than a single head-to-head study