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They found that GLP-1 use was associated with about 7 fewer people per 1,000 developing any substance-use disorder over the study period of three years

However, it should be noted that the reductions were more pronounced in male rats than in female rats (Vallof et al., 2020), suggesting that sex differences in treatment outcome should be further evaluated in upcoming studies
It is important to note that permitted application sites vary significantly between different transdermal medications
