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Description
Learn how weight bias drives disengagement, inequity, and wasted healthcare spend.

While first- and second-generation options only target one or two of these pathways, Retatrutides triple-action mechanism completely redefines what is possible for chronic weight management and metabolic restoration

Method We systematically searched PubMed and Embase from inception to 1 May 2025 for cohort studies comparing the effect of combination therapy with SGLT2 inhibitor or GLP-1 RA monotherapy on (cardiovascular) mortality and cardiovascular or kidney endpoints in individuals with type 2 diabetes
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