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Description
In the STEP 1 semaglutide trial (Wilding et al., NEJM , 2021) and the SURMOUNT-1 tirzepatide trial (Jastreboff et al., NEJM , 2022), nausea affected roughly 44% of semaglutide patients and about 24% of tirzepatide patients at the maximum dose
Cancellation is available at any time with a 72-hour notice before the next billing date

People with IBS, especially those with constipation-predominant symptoms or a history of post-infectious IBS, may already have altered gut motility, which could increase vulnerability

For most people, yes, if their doctor has cleared them for exercise
