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This was shown in a study of 86,000 adults with obesity

Semaglutide subcutaneous formulation proved efficacious across SUSTAIN trials

Pharmacological management of obesity: An endocrine society clinical practice guideline

Select your current weight 286 pounds 130 175 220 265 310 355 395 440 Weight you could lose 57 pounds *In a 68- and 72-week clinical trial studying Wegovy (2.4 mg) and Zepbound (15 mg) in patients without diabetes and with BMI 30, or BMI 27 with a weight-related condition, the average weight loss was 15% and 20%, when paired with diet and exercise changes (compared to 2.4% and 3.1%, respectively, with diet and exercise alone)