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doi: 10.3389/fendo.2018.00672 [DOI] [PMC free article] [PubMed] [Google Scholar] 114

Thus, incubating human and rodent islets under high glucose conditions results in increased expression of PC1/3 and increased secretion of GLP-1 (101, 108110), while exposure of -cells to the proinflammatory cytokine, interleukin-6, also increased GLP-1 secretion (112)

Department of Neurology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, B15 2GW, UK