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In the report, two patients on glucagon-like peptide 1 (GLP-1) agonists had significant gastric contents during elective gastroscopy despite adequate fasting

doi: Mennella I, Fogliano V, Ferracane R, Arlorio M, Pattarino F, Vitaglione P

Among the GLP-1RAs, exenatide is the synthetic version of exendin-4, a molecule identified in the Gila monster salivary gland whose amino acid sequence shares 53% identity with human GLP-1

An exploratory mediation analysis of the effects on kidney outcomes (composite of macroalbuminuria, decreased GFR, renal death) with liraglutide and semaglutide in patients with T2DM in the LEADER and SUSTAIN-6 trials observed that HbA1c mediated 2526% and SBP 922% of kidney effects with a negligible contribution of the other parameters studied, such as body weight [15]