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Description
Muscle quality, insulin sensitivity, mitochondrial efficiency, intramuscular fat , may actually improve on GLP-1 therapy
This article reviews the efficacy and safety of different strategies to initiate and intensify basal insulin, with focus on new fixed ratio combinations of basal insulin with GLP-1 RAs available for use in a single injection pen (insulin degludec/liraglutide and insulin glargine/lixisenatide).
Trial registration NCT02723110, NCT02465515 and NCT01144338.
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