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Description
All cells take advantage of an array of mechanisms to preserve the stability and functionality of their proteins or to remove them when they are irreversibly damaged

The medication's effect on gastric emptying can exacerbate pre-existing gastroesophageal reflux disease (GERD), potentially causing retrosternal burning or pressure that mimics cardiac symptoms
While regulatory agencies always review reports on any medication, the most common side effects are well-documented and manageable under a doctors care

No adverse developmental effects were observed when sitagliptin was administered to pregnant rats and rabbits during organogenesis at oral doses up to 30-times and 20-times, respectively, the 100 mg clinical dose, based on AUC [see Data]
